Jack's autopsy pictures


Jack

Chest cavity with heart and fat.




Jack

Heart and lungs surrounded by fat.




Jack

Abdominal cavity with fat and tumour in the middle.




Jack

Fat deposit in abdomen.




Jack

Location of kidney surrounded by fat.




Jack

Kidney surrounded by fat.




Jack

Kidney surrounded by fat and tumour surrounded by fat.




Jack

Intestine with tumour and another mass.




Jack

Intestines with fat on mesenteric membrane.




Jack's histopathology report:

History Difficulty breathing, very enlarged abdomen (6-10 months). Sudden deterioration over last 24 hours. Euthanased. PM - Fat, large amounts in abdomen & chest especially around kidneys, also mesentery, bladder/uterus.

Diagnosis Pancreatic Endocrine Tumour - “Insulinoma” and Interstitial Pneumonia

Prognosis Prognosis Not Given

Commentary

Spleen: There is marked splenic congestion and some haemorrhage. No evidence of neoplasia.
Pancreas: There is a large well vascularised mass comprising cords and packets of pleomophic polygonal cells with marked nuclear atypia and variable fine cytoplasmic vacuolation.
Adipose tissue adjacent to pancreas and within mesentery: This contains small accessory spleens and several small to large nodules (up to 1.5cm) of neoplasia as described in the pancreas.
Heart: Normal.
Lungs: Congested and collapsed with accumulation of mixed inflammatory cells within the interstitium.
Kidneys: Largely within normal and expected to have been functioning antemortem.

COMMENTS:
The changes are consistent with a malignant tumour arising from islet cells (insulinoma) with metastatic spread and an intersitial pneumonia. The cause of the latter is not apparent from the histological features.